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速递书局
封面: |
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题名: |
Glycosylation Engineering of Biopharmaceuticals |
作者: |
Alain Beck |
出版社: |
Humana Press |
出版日期: |
2013-03-09 |
ISBN: |
9781627033268 |
附属页: |
齐全 |
书签: |
有 |
格式: |
清晰PDF |
内容简介: |
Glyco-engineering is being developed as a method to control the composition of carbohydrates and to enhance the pharmacological properties of monoclonal antibodies (mAbs) and other proteins. In Glycosylation Engineering of Biopharmaceuticals: Methods and Protocols, experts in the field provide readers with production and characterization protocols of glycoproteins and glyco-engineered biopharmaceuticals with a focus on mAbs. The volume is divided in four complementary parts dealing with glyco-engineering of therapeutic proteins, glycoanalytics, glycoprotein complexes characterization, and PK/PD assays for therapeutic antibodies. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. |
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