标题: Methodologies for Metabolomics : Experimental Strategies and Techniques+ PDF+50 [打印本页] 作者: eli.123 时间: 2013-2-20 17:01 标题: Methodologies for Metabolomics : Experimental Strategies and Techniques+ PDF+50 本帖最后由 flyingowl 于 2013-2-20 17:46 编辑
Title: Methodologies for Metabolomics : Experimental Strategies and Techniques Print ISBN: 9780521765909
Author(s): Lutz, Norbert; Sweedler, Jonathan; Wevers, Ron eISBN: 9781139615334
Publisher: Cambridge University Press
Series: Publication Date: 31 Dec, 2012
Pages: 642
LCCN: Language: English
Metabolomics, the global characterisation of the small molecule complement involved in metabolism, has evolved into a powerful suite of approaches for understanding the global physiological and pathological processes occurring in biological organisms. The diversity of metabolites, the wide range of metabolic pathways and their divergent biological contexts require a range of methodological strategies and techniques. Methodologies for Metabolomics provides a comprehensive description of the newest methodological approaches in metabolomic research. The most important technologies used to identify and quantify metabolites, including nuclear magnetic resonance and mass spectrometry, are highlighted. The integration of these techniques with classical biological methods is also addressed. Furthermore, the book presents statistical and chemometric methods for evaluation of the resultant data. The broad spectrum of topics includes a vast variety of organisms, samples and diseases, ranging from in vivo metabolomics in humans and animals to in vitro analysis of tissue samples, cultured cells and biofluids.